Natural progesterone is the new hormonal darling of the perimenopausal
set, and well
deserving of its status. Women like to take it. It lightens heavy menstrual
flow,
soothes and softens tender hard breasts, acts like a mild tranquilizer,
makes you
sleep like a rock, and relieves water retention. The perfect antidote to
PMS and
anovulatory periods, its main drawback until recently was how difficult
it was to
administer.
All hormones, taken orally, are delivered straight to the liver where they
are rather
efficiently broken down. First given by painful injections for threatened
miscarriages,
progesterone was then prescribed in a variety of ways for PMS, including
by rectal
suspension and vaginal suppositories. No wonder that women did not rush
to
embrace these preparations. More recently, progesterone has become widely
available as a skin cream, sold over the counter. Just like the estrogen
skin patches,
progesterone absorbed through the skin is not first passed through the
liver so it is
more readily available for use by the body. In the last year, a major pharmaceutical
company has suspended micronized progesterone in peanut oil in a new,
well-absorbed, oral preparation called Prometrium.
There is sound justification for the use of natural progesterone in perimenopause
for
heavy periods, tender breasts, bloating and irritability. There is evidence
that it can
diminish hot flashes and prevent osteoporosis. There have been claims that
it will
restore thinning hair and flagging sexual interest, as well as improve
arthritis,
allergies, skin problems, and high blood pressure. It is not clear that
natural
progesterone can deliver on these counts.
Synthetic versions of progesterone, called progestogens, have been used
along with
estrogen to protect the uterus in post-menopausal women on hormone replacement
therapy (HRT). Unfortunately, no one likes to take these drugs (brand names
Provera
, Cycrin and Aygestin). Their side effects of bloating and depression are
one of the
main reasons that women give up on HRT. The availability of Prometrium
has greatly
improved the choices for combination hormone therapy.
Natural progesterone cream comes in many different strengths but you should
seek
a brand that provides about 1,000 mg. in 2 oz. cream. Small quantities,
1/4 - 1/2 teaspoonfuls,
are rubbed twice daily on the inner arms, thighs, abdomen, or chest, from
mid-cycle
until menstruation. Do not buy wild yam cream; the body cannot utilize
it to make
progesterone.
The cream cannot be relied upon to protect your uterus from the effects
of
supplemental estrogen. In this post-menopausal setting, you must use the
oral
preparations to be safe. Progesterone levels in your body are higher on
an oral dose
than with the skin cream. Some women notice an anti-anxiety effect, or
even a
drunken, sleepy feeling from its direct, anesthetic effects on the brain.
This information is
intended to be general in nature and should not be relied upon
for specific treatment.
If you need medical attention, please contact your personal
physician's office for an appointment.
Read many more of Dr. Paley's articles
at: http://www.femailhealthnews.com
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